Understanding the Molecular Mechanisms Underlying the Analgesic Effect of Ginger

Chronic pain has a high prevalence and profound impact on patients society, its treatment is real challenge in clinical practice. Ginger emerging as promising analgesic—effective against various types of well-tolerated by patients. However, we are just beginning to understand complex mechanism action. A good understanding would allow us fully utilize the therapeutical potential this herbal medicine well identify better strategy for treating chronic pain. To provide information, searched PubMed, SCOPUS, Web Science vitro studies or animal experiments investigating analgesic effect ginger extract components. The analysis data was carried out form narrative review. Our research indicates that extract, through active ingredients, suppresses transmission nociceptive signals while activating descendent inhibitory pathways